How do you solve a puzzle with hidden pieces? That’s the question researchers focused on pediatric Inflammatory bowel disease (IBD) face every day, as only 20% to 25% of their young patients under 5 years old present with a diagnosis-confirming genetic factor. Identifying the remaining children with the serious disorder presents a vast challenge.
Then the issue becomes: What’s the best treatment option for each patient, based upon their personal genetic markers? Gains are being made in personalized and immunologic therapies for IBD patients – essentially activating or educating the young patient’s own immune system against the disease – but much remains to be learned.
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